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Filed Under: HEALTH, PROJECTS

Gold Coast accelerates as a clinical trial hub during COVID-19 times

Griffith University's Clinical Trials Unit (CTU)

Business at Griffith University’s Clinical Trials Unit (CTU) has not only continued but thrived in the midst of a pandemic, with the site being first globally to recruit patients for a multi-national rheumatology trial and screening the first patient in Australia for another multi-national trial.

The Gold Coast and Queensland have benefited from the state’s current low COVID-risk status, to accelerate capability that had been rapidly building, pre-pandemic.

Australia's largest regional clinical trials location - and growing

A 2019 study, commissioned by the Gold Coast Health and Knowledge Precinct, Regional Development Australia (RDA) Gold Coast and the Queensland Government Department of State Development, Tourism and Innovation, found the Gold Coast was Australia’s largest regional clinical trial location, with 126 trials contributing almost $12 million per annum to the city’s economy, and significant growth anticipated over the coming decade.

Director of the Griffith University Clinical Trial Unit, Professor Evelin Tiralongo, said growth could be even stronger than earlier projections of the local sector being worth $33 million by 2029, with further demand likely to be caused by the pandemic.

“Providing high-quality clinical trial services to global and national sponsors, as well as supporting researcher-led trials, is core business for us, and being able to operate in a COVID-safe way, in an environment with so far low levels of coronavirus in the community in Australia, Queensland, and the Gold Coast in particular, is an advantage,“ Professor Tiralongo said.

Professor Evelin Tiralongo

“After some initial disruptions to active trials, we worked very quickly on setting up a COVID-19 safe plan to enable us to continue providing essential services for existing clinical trials and subsequently take on new business, with great support from the University, our External Advisory Committee and the clinicians and other health professionals we work with.”

With intense focus on multiple COVID-19 trials worldwide, researchers, including Griffith’s Professor Michael Good AO, Principal Research Leader at the Institute for Glycomics and a member of the Australian Government’s National COVID-19 Health and Research Advisory Committee, continue to press the need for vital research and trials into other important conditions to continue, or risk significant health consequences.

Professor Michael Good

Many such important trials are currently being conducted at Griffith’s Clinical Trial Unit in areas such as rheumatology, neurology, endocrinology, renal disease, gastrointestinal disorders and infectious diseases, with the unit looking to expand into dermatology and cardiology.

Dr Claire Williams, the Clinical Trial Unit’s Business and Operations Manager, has welcomed the opportunity to take part in these studies and expand the CTU’s business.

“Despite everyone’s attention being currently focussed on COVID-19, it’s still vitally important that we continue to develop and improve vaccines and treatments for other chronic and serious diseases. As a University Core Research Facility, it is crucial to continue to support Griffith researcher-led trials and take on pharma trials so that we can enhance clinical research and knowledge and offer possible new therapy options to the Gold Coast community,” said Dr Williams.

“We are undertaking trials which focus on outpatients and greatly value the continuous and growing collaboration with clinicians from General Practice, Specialised Private Practice, the Gold Coast Hospital and Health Service and other providers. Being in the same building as the Griffith’s Health Clinics and Menzies Health Institute Queensland makes it easy to collaborate with other Allied Health professionals and researchers.”

Clinicians who would like to collaborate on current and planned trials at Griffith’s CTU should contact CTU management for further information [email protected] and volunteers can register their interest via the CTU’s website here.

October 29, 2020 By Kathy Kruger

Filed Under: BUSINESS, People of the Precinct, Research

People of the Precinct – discovering an ocean of possibilities through data science

Dr Stephanie Chaousis is connecting academia, industry and healthcare to the power of AI and data science

With technology company Datarwe opening its doors to a new DataScience lab within Cohort in the Gold Coast Health and Knowledge Precinct, it can accelerate development of its Precision Medicine Data Platform (PDMP), a world-leading comprehensive acute care medical research platform – providing a major new resource to develop AI enabled diagnostics, treatment protocols and med-tech products in Queensland.

Driving partnerships and engagement, including a major partnership with Griffith University, is former alumnus Dr Stephanie Chaousis, an Ecotoxicology PhD whose own research saw her wading through a sea of data to develop a keen appreciation for the potential of AI and machine learning.

When Stephanie Chaousis undertook her undergraduate marine and molecular science studies at James Cook University, before completing post-graduate honours exploring therapeutic effects of jellyfish venom at the Australian Institute of Tropical Health and Medicine in 2012, the opportunities presented by the next-generation of artificial intelligence (AI) may still have seemed oceans away, for novice researchers like herself.

Only eight years ago the potential of AI and machine learning for researchers, industry and indeed the whole world, was being rapidly developed in university computer science labs, tech companies and major corporations, but the ripple effect on research in other scientific fields was still to be fully felt.

Steph’s jellyfish project called for separating out multiple different molecules to determine which were lethal and which weren’t, in the hunt for those that might prove therapeutic – painstaking laboratory analysis performed without the help of a handy predictive algorithm.

After a short segue at the University of Queensland’s Institute for Molecular Bioscience, probing therapeutic opportunities in Tarantula venom, Steph embarked on a PhD at Griffith University in 2015, in a bid to discover a protein biomarker for exposure to chemical pollution from the cell and blood samples of sea turtles.

By the time she was completing her final thesis to earn her doctorate and play her part in marine conservation, she had some 200,000 data points to work with, and was convinced of the opportunity that AI presents in an increasingly ‘big data’ world.

Steph (right) with research colleagues during her PhD at Griffith University

“When you have too much data it becomes more challenging to derive meaning, so I got really interested in AI and machine learning from that point.”

Having worked in both lab and teaching assistant roles at Griffith throughout her PhD studies, Steph proved her versatility by finding a position as an Environmental Scientist for the City of Gold Coast’s Water and Waste directorate, while simultaneously interning with Griffith’s Institute for Glycomics as a Business Analyst.

She’d previously connected with Datarwe CTO Dr Kelvin Ross at a Cohort event, and kept in touch, so he came knocking when the fast-growing company needed an energetic exponent of Data Science and AI, who could build collaboration with researchers in industry, academia and healthcare.

“It’s really exciting to be working with Datarwe from such an early stage and being a part of the company’s growth. Being in this space has offered up great opportunities such as developing and overseeing the MedTech Program for the new Queensland AI Hub, which is a dual role I’m currently in,” Steph says.

“What’s exciting about AI is that it can provide us with accurate prediction using insights from the medical data we already have access to – so rather than relying on future studies and trials, we can look retrospectively for clues and answers. But in order to extract this meaning, the data needs to be useable, accessible, accurate and secure, which is what we are doing at Datarwe by building the PMDP.”

The Datarwe data science technologies lab at Cohort

Datarwe’s PDMP, which earlier this year received $1.5 million funding from Advance Queensland, works by collecting de-identified patient data from hospital Intensive Care Units’ monitoring devices and clinical notes. The data is securely enriched so it can be used by developers to create tools using AI and ML to develop predictive analytics, which then help health care professionals make timely decisions at the patient’s bedside.

It’s a potentially life-saving platform, especially in the midst of a pandemic, and Steph was eager to inspire innovation, as chair of the inaugural Queensland AI Hub Medical Datathon, held in virtual mode in July.

Staged over two weekends, the event brought together multidisciplinary teams with expertise in data science, ML and AI, with clinicians and medical researchers, as well as the business and student communities, to work with real-world data on new medical applications. The impact has extended well beyond, with many teams continuing to develop their projects to make waves in the world of AI – read more.

“Overall, the last 6 months working at Datarwe and the AI Hub has opened my eyes to the appetite in Queensland, and particularly the Gold Coast, for the kind of advanced technology we are building at Datarwe and supporting through the Hub.

As I have personally experienced, the job opportunities in this space are growing rapidly right here in the GCHKP and Lumina, and I’m glad to be able to support the growth of this important industry for Queensland.”

Connect with Steph

October 29, 2020 By Kathy Kruger

Filed Under: STUDY, TECHNOLOGY Tagged With: Cohort, Griffith University, NASA, Space Apps Challenge

People of the Precinct – career rockets to new heights

Dominique MacDonald overseeing NASA Space Apps Challenge Gold Coast 2020

Dominique MacDonald makes most of stellar opportunities

Griffith University engineering student leader Dominique MacDonald is set to complete a stellar four years of undergraduate studies, including STEM ambassadorships and industry placements, but not before taking her ambitions to new heights as host of the Gold Coast NASA Space Apps Challenge – part of the world’s largest global hackathon.

With 16 months experience as an R&D software developer for a Gold Coast biotech company already under her belt, and a graduate position as a robotics engineer at global mining giant Rio Tinto in her back pocket, the former Griffith Women in Engineering president has left little unaccomplished, turning to space as a new frontier.

Flying solo as lead for the inaugural local event, which she ran in virtual mode on-line from the Gold Coast Health and Knowledge Precinct’s Cohort Innovation Hub (3-4 October), Dominique wasn’t sure what to expect from challenge participants, other than out-of-this world ideas.

READ MORE about the Space Apps Challenge

October 28, 2020 By Kathy Kruger

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Latest News

From Research to Reality: GCHKP Talent Leads the LuminaX 2025 Cohort image

From Research to Reality: GCHKP Talent Leads the LuminaX 2025 Cohort

Read More >

A New Era of Health and Tech Innovation: HATRIC to Transform the Gold Coast image

A New Era of Health and Tech Innovation: HATRIC to Transform the Gold Coast

Read More >

Clinician Entrepreneurship Program wraps as a big success image

Clinician Entrepreneurship Program wraps as a big success

Read More >

2025 International Women's Day image

2025 International Women's Day

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International Women's Day event 2025 image

International Women's Day event 2025

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Associate Prof Lara Herrero leading the fight against mosquito-borne diseases and advancing medical research image

Associate Prof Lara Herrero leading the fight against mosquito-borne diseases and advancing medical research

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